On April 25, the House Foreign Affairs Subcommittee on Africa and Global Health heard testimony on initiatives to combat malaria. Particular attention was given to the deadly effects of the disease on pregnant women and young children.
Chair Donald Payne (D-NJ) stated, “Pregnant women and children are, in fact, the most vulnerable when it comes to malaria. Malaria kills an African child every 30 seconds, causes between 20 percent and 25 percent of all deaths among African children under five-years, and constitutes 10 percent of the continent’s overall disease burden. Malaria has also been cited as a significant indirect cause of death. In sub-Saharan Africa, health experts contend that malaria contributes to anemia in pregnancy, low birth weight, and premature delivery, which, combined, kill from 75,000 to 200,000 infants each year. These statistics are absolutely staggering. They remind us that we simply are not doing enough to fight malaria.”
Admiral Timothy Ziemer, USN, (Retired), coordinator of the President’s Malaria Initiative (PMI) at the U.S. Agency for International Development, detailed PMI’s efforts to fight malaria since 2005. Noting that “infection during pregnancy poses serious health risks for both the mother and her unborn child,” he said, “Malaria may be transmitted from mother to fetus before or during labor and delivery. If a pregnant woman contracts malaria, she is at much greater risk of anemia, premature delivery, and death. In addition, because malaria parasites sequester in the placenta and impair the delivery of nutrients to the growing fetus, a mother’s newborn child is at higher risk of low birth weight a leading cause of poor infant survival in Africa. The prevention and treatment of malaria during pregnancy depends on a combination of malaria control measures, including the use of ITNs [Insecticide Treated Mosquito Nets], laboratory diagnosis for prompt and effective treatment, and intermittent preventive treatment.”
Admiral Ziemer explained that intermittent preventive treatment of pregnant women (IPTp) “is a highly effective means of reducing the risk of malaria in pregnant woman and the adverse consequences to her unborn child. It involves the administration of at least two treatment doses of an antimalarial drug, sulfadoxine-pyrimethamine, to the woman during the second and third trimesters of her pregnancy with at least a one-month interval between doses. IPTp reduces the frequency of maternal anemia, malaria infection of the placenta, and the delivery of low birth weight babies. Because in most African countries more than 70 percent of pregnant women attend antenatal clinics, these clinics serve as an attractive platform for delivering preventive treatments. The wide-scale use of IPTp could prevent up to 75,000-200,000 infant deaths each year in Africa.” He cited the importance of artemisinin-based combination therapies (ACTs), and added, “To prevent malaria in pregnant women and reduce the incidence of life-threatening low birth weight among newborns, PMI has supported IPTp. In total, more than 10,000 health providers have already been trained in these critical interventions with PMI support.”
Outlining the role of ITNs, Admiral Ziemer noted that “ITNs have been shown to reduce all-cause mortality in children under five by about 20 percent and malarial illnesses among children under five and pregnant women by up to 50 percent.” He said that in Tanzania, “beginning in mid-December 2005, PMI distributed 130,000 free long-lasting ITNs (233,000 total with contributions by the GFATM [Global Fund to Fight AIDS, TB, and Malaria]) through local health clinics, more than doubling existing ITN ownership rates among pregnant women and children under age five on Zanzibar and Pemba Islands.” In northern Uganda, where there are “alarming rates of malaria mortality in internally-displaced person camps,” Admiral Ziemer said that “PMI distributed over 300,000 free long-lasting ITNs to children and pregnant women.”
Admiral Ziemer specified PMI goals for “children under age five and pregnant women. These include:
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